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Studies

Study on the efficacy of LITOVET

Study on the efficacy of LITOVET

74 horses, all trotters, were included in a double-blind, placebo controlled trial. The horses were randomized in blocks of three of which two received LITOVET® and one placebo of similar taste and colour. Then the LITOVET® group, as well as the placebo group, were treated for three months.

Question of the study

Does LITOVET®, a herbal remedy made from Rosa Canina, act as an anti-inflammatory agent in horses exposed to strenuous exercise? A randomized, placebo-controlled, parallel, double-blinded study on the immune system of horses, their working capacity and behavior. K.Winther, J. Falk-Rønne, A. Kharazmi, A.V. Hansen, and E.W. Hansen. Department of Clinical Biochemistry, Frederiksberg Hospital, University of Copenhagen, The Horseclinic at Lunden, Charlottenlund, Copenhagen, Department of Clinical Microbiology, Rigshospitaltet, University of Copenhagen, Denmark.

Introduction and Aim

A standardised product, LITOZIN®, made from rose hip (Rosa Canina), has shown anti-inflammatory and pain reducing properties in humans. The present study aimed to test if LITOVET®, a version of LITOZIN® especially developed for horses, would affect the immune system, working capacity and behaviour of horses.

Delta Change in time to run 1000 meters

Chart: improved time to run 1000 meters with LITOVET

Delta change in time to run 1000 meters. Horses treated with LITOVET® or placebo. During LITOVET® treatment the horses improved their speed. (p<0,02)

Chemotaxis

Chart: improved time to run 1000 meters with LITOVET

Neutrophile leucocyte chemotaxis in horses before and after treatment with LITOVET®. Three months treatment with LITOVET® resulted in a significant reduction in chemotaxis.

Chart: significant reduction in chemotaxis with LITOVET

Neutrophile leucocytes chemotaxis in horses before and after 3 months treatment with LITOVET® and again 3 months after withdrawal of therapy. LITOVET® resulted in a significant reduction in chemotaxis. 3 months after withdrawal this reduction was reduced by 50 percent.

Vitamin-C levels in horses

Chart: increased vitamin-C Level on LITOVET

Vitamin-C levels in horses following intake of 25, 50 oder 100 g of LITOVET® per day. A significant increase in vitamin-C was observed in blood drawn from horses after 4 and 12 weeks.

Study on the efficacy of LITOPET

Study on the efficacy of LITOPET

68 greyhounds were randomly allocated to either LITOPET® or placebo treatment for a three-month period. The animals were randomized in blocks of three with two dogs given LITOPET® 10 gram daily as a dry powder added to the food and one dog given the same amount of placebo powder with a similar taste, odour and colour.

Question of the study

A herbal remedy derived from a subspecies of Rosa Canina, improves the immune response, working capacity and well-being of dogs. A parallel, placebo controlled, double-blind, randomized study. A. Ragone, A. S. V. Hansen, P. Hansen, A. Kharazmi: Department of Clinical Biochemistry, Frederiksberg Hospital and K. Winther: Department of Clinical Microbiology, Rigshospitalet, University of Copenhagen, Denmark.

Introduction and Aim

LITOZIN®, a standardised product made of 100% rose hip (Rosa Canina), produced by Hyben Vital®, has shown anti-inflammatory and soothing properties in humans. The present study aimed to test whether the same powder might improve the immune response, working capacity and well-being of dogs.

Chemotaxis

Chart: strongly inhibited chemotaxis in neutrophils on LITOPET

In vitro neutrophil chemotaxis before and after the addition of LITOPET®. "LITOPET® strongly inhibits chemotaxis in neutrophils."

Leucocyte count

Chart: significant decline in total ?leucocyte count

Influence of three month treatment with 10 g LITOPET® per day on leucocytes of Greyhounds. "3 month treatment resulted in a significant decline in total leucocyte count."

Fur quality

Chart: improved quality of fur on LITOPET

"Quality of the fur improved from 3 months LITOPET® treatment."

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